Ogwumike, who entered the game averaging 21.9 points and 12.2 rebounds, also had a career-high five assists for the Cardinal (11-0).
Amber Orrange scored 14 points, Toni Kokenis and Bonnie Samuelson each added 11 points and Joslyn Tinkle had 10 points for the Cardinal, who host No. 2 Connecticut in their next game Dec. 29.
Bashaara Graves had 15 points and 12 rebounds for Tennessee (7-3). Meighan Simmons added 12 points, while Ariel Massengale and Cierra Burdick had 11 points each.
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