Jalan McCloud added 12 points with six assists and Peter Jurkin had 10 points for the Buccaneers (5-3), who lost their season opener to the Norse (6-3) in a rare home-and-home nonconference series.
In the first meeting ETSU had 20 turnovers and three assists. The Buccaneers finished 17 assists and 10 giveaways on Wednesday.
Jason Williams had 3-pointers to start and end a 15-0 run for a 22-9 lead. The Norse quickly responded with a 9-0 spurt but ETSU closed the half with a 20-5 run and a 46-28 lead.
The Bucs shot 59 percent (16 of 27) in the first half, then shot 60 percent in the second half.
Northern Kentucky had an 11-4 run to get within a dozen points midway through the second half but ETSU pulled away again.
Carson Williams had 22 points on 10-of-13 shooting for Northern Kentucky.
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