Both Burkhead and Gillislee are out with knee injuries. With them out, the primary rushing duties will fall to Dion Lewis and James White.
Other New England players inactive for the matchup are defensive lineman Alan Branch (knee), receiver Kenny Britt, offensive lineman Cole Croston, linebacker David Harris and cornerback Johnson Bademosi.
Running back DeMarco Murray is out for the Titans with a knee injury. Joining him on their inactive list are third-string quarterback Brandon Weeden, running back Khalfani Muhammad, defensive back Curtis Riley, linebacker Josh Carraway, offensive lineman Corey Levin and defensive end David King.
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